Jukka Jernvall

Jukka Jernvall (born 1963) is a Finnish Academy professor [1] at the University of Helsinki.[2] He is an elected member of The Finnish Academy of Science and Letters (Suomalainen tiedeakatemia) and The Finnish Society of Science and Letters (Finska Vetenskaps-Societeten). His research centers around the interplay of ecology, evolution and developmental biology, especially of the mammalian dentition. He is in the international forefront in evo-devo research.[3]

Jernvall received his Ph.D. in evolutionary biology in 1995. His thesis investigating the evolution and development of mammalian molar cusp patterns was supervised by Irma Thesleff and Mikael Fortelius. This led to the description of enamel knot as molecular signaling centers in teeth. He also discovered and coined the term ‘secondary enamel knot’, previously overlooked signaling centers regulating tooth cusp development. This discovery helped to mechanistically link molecular regulation of growth and differentiation to shape. Later, Jernvall has focused on the modelling of three-dimensional dentition phenotypes. He has studied why certain dentition patterns arise several times during the course of evolution, while other patterns occur only rarely. Jernvall's team has developed several methods from computer modeling of organ development to three-dimensional analysis of biological shape development and function.[4] The science journal Nature described his and his two post doc researchers’ studies of dentition evolution as some of the most significant pieces of evolutionary research of the “recent decade or so.”[5]

At the moment, Jernvall leads his research group in the Institute of Biotechnology, University of Helsinki and is also a research professor at Stony Brook University, NY, USA.[6] The current research of his team ranges from mutant mice in the laboratory to evolutionary diversity in the fossil record and to the senescence of wild mouse lemur populations in the Ranomafana National Park in Madagascar.

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